Pelvic (inferior hypogastric plexus) intramural ganglia

Ganglion · Inferior hypogastric plexus S2–S4 input

Pelvic splanchnic nerves synapse in ganglia scattered through the inferior hypogastric (pelvic) plexus on the pelvic side wall and within the walls of the bladder, rectum, uterus and erectile tissue. Fibres for the descending and sigmoid colon ascend through the hypogastric nerves to synapse in the hindgut wall.

Traced from the start

  1. Parasympathetic (craniosacral) outflow
  2. Sacral parasympathetic outflow S2–S4 (pelvic splanchnic nerves)
  3. Pelvic (inferior hypogastric plexus) intramural ganglia

Detail

Location
Either side of the rectum, alongside the seminal vesicles or uterine cervix — within reach of pelvic surgery
Hindgut extension
Preganglionic fibres ascend via hypogastric nerves and superior hypogastric plexus to ganglia in the descending and sigmoid colon
Cavernous nerves
Leave the plexus beside the prostate to reach the corpora cavernosa

When it goes wrong

Failure of neural crest cells to migrate into the distal bowel wall (Hirschsprung disease, RET mutations)

Aganglionic rectosigmoid segment stays contracted: failure to pass meconium within 48 hours, abdominal distension and bilious vomiting; rectal biopsy shows absent ganglion cells with hypertrophied nerve trunks

Radical prostatectomy, abdominoperineal resection or radical hysterectomy damaging the pelvic plexus

Erectile dysfunction and bladder dysfunction (retention or poor emptying) from loss of parasympathetic supply

Practise this structure

1 question in the bank tagged Autonomic.