Arrector pili muscle
Hypodermis & appendages · detail · α1 adrenergic Piloerection Bulge niche
Small band of smooth muscle running from the follicular bulge to the papillary dermis. Sympathetic adrenergic stimulation contracts it to erect the hair, and its insertion marks the follicular stem cell niche.
Traced from the start
Detail
- Innervation
- Sympathetic noradrenergic fibres acting on alpha-1 receptors; no parasympathetic supply
- Attachment
- Runs from the bulge region of the follicle to the papillary dermis, defining the position of the stem cell niche
- Function
- Piloerection; vestigial for insulation in humans but a reliable marker of sympathetic outflow
When it goes wrong
Interruption of the sympathetic supply to the face (central or preganglionic Horner syndrome)
Ipsilateral ptosis, miosis and facial anhidrosis with loss of piloerection; a painful Horner syndrome demands urgent imaging for carotid dissection
Adrenergic surge in opioid withdrawal
Piloerection with lacrimation, rhinorrhoea, yawning, mydriasis and diarrhoea — the classic withdrawal cluster
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