Meissner corpuscle

Papillary dermis · detail · Rapidly adapting I Light touch Fingertips

Encapsulated rapidly adapting type I mechanoreceptor packed into the dermal papillae of glabrous skin, signalling light moving touch and low-frequency flutter through A-beta fibres.

Traced from the start

  1. Stratum basale (germinativum)
  2. Lamina densa (type IV collagen basement membrane)
  3. Meissner corpuscle

Detail

Modality
Light dynamic touch and flutter at roughly 5-50 Hz; adapts within milliseconds so it reports change, not steady pressure
Distribution
Glabrous skin only, densest at the fingertips and lips, matching the two-point discrimination gradient
Afferent
Large myelinated A-beta fibres travelling in the dorsal column-medial lemniscus pathway

When it goes wrong

Age-related loss of corpuscles and of A-beta fibres

Falling fine touch acuity and widening two-point discrimination, contributing to loss of manual dexterity and to falls in the elderly

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