Ductus venosus

Venous return · SaO2 ~80% Bypasses liver

Narrow, trumpet-shaped shunt from the umbilical vein and left portal vein to the IVC just below the diaphragm. It bypasses the hepatic sinusoids and delivers a fast, well-oxygenated jet that is aimed at the foramen ovale.

Traced from the start

  1. Placenta
  2. Umbilical vein
  3. Ductus venosus

Detail

Saturation
~80%, essentially undiluted umbilical venous blood
Shunt fraction
Textbooks quote about half of umbilical venous flow; human Doppler studies show ~30% at 20 weeks falling to ~20% at term, rising again with hypoxia
Regulation
Sphincter-like inlet under adrenergic, nitric oxide and prostaglandin control; dilates during hypoxaemia to boost shunting to heart and brain
Streaming
Its high-velocity stream stays separate from the slow, desaturated abdominal IVC blood and is directed by the eustachian valve and crista dividens across the foramen ovale
Closure
Functionally closed in most infants by 1-2 weeks; fibroses to the ligamentum venosum by ~2-3 months (hover to see)

When it goes wrong

Fetal hypoxaemia or growth restriction on Doppler surveillance

Shunting through the ductus venosus increases to protect heart and brain; an absent or reversed a-wave (atrial contraction) signals cardiac decompensation and is used to time delivery

Reversed ductus venosus a-wave at the 11-13 week scan

Marker of trisomy 21 and major cardiac defects in first-trimester screening

Practise this structure

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