Psychiatry and Mental Health practice

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Psychiatry and Mental Healthmiddle twist

A 48-year-old man presents with severe persecutory psychosis and requires medication after verbal de-escalation has failed. He has no history of cardiac disease, but his ECG shows a QTc of 530 ms (less than 450 ms), and his potassium is 3.8 mmol/L (3.5–5.2) after replacement. He is not taking any other medicine known to prolong the QT interval. Which one of the following antipsychotics is the most appropriate choice?