Acute Caremiddle twist
A 74-year-old man on the orthopaedic ward is found drowsy six hours after his first dose of slow-release oxycodone for a fractured neck of femur. He rouses briefly to a loud voice, his respiratory rate is 6/min, oxygen saturation 90% on 6 L/min and his pupils are 1 mm. He has stable angina and a myocardial infarction four years ago. A nurse is assisting his breathing with a bag and mask and the medical emergency team has been called. Which one of the following naloxone regimens should he be given first?