Gout and hyperuricaemia practice

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Rheumatology and Musculoskeletalcommon

A 58-year-old man develops severe pain and swelling at the base of his right great toe overnight. He is afebrile and has no skin wound or prosthetic joint. Synovial fluid contains needle-shaped crystals that are strongly negatively birefringent under polarised light, and culture shows no organisms. Which is the most likely diagnosis?