Cardiovascularmiddle twist
A 68-year-old man with metastatic oesophageal cancer develops a symptomatic proximal deep vein thrombosis. He completed treatment for melaena from the tumour two weeks ago; endoscopy now shows no active bleeding, and his haemoglobin is stable. He has normal renal function and no previous venous thromboembolism. Which one of the following is the most appropriate anticoagulant?