Paediatricsmiddle twist
A 15-year-old boy weighing 60 kg presents to a metropolitan emergency department six hours after swallowing forty paracetamol 500 mg tablets in one go. He has vomited twice and is otherwise well. His serum paracetamol concentration, taken four hours after ingestion, is above the nomogram treatment line but less than twice it, and his liver biochemistry and international normalised ratio are normal. Intravenous access is established. Which one of the following acetylcysteine regimens should he be started on?