Tricyclic antidepressant and serotonergic toxicity practice

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Tune this setClinical rotations · 20 questionschange

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Emergency and Toxicologycommon

A 32-year-old man is found confused after ingesting an unknown number of amitriptyline tablets. He has a blood pressure of 86/54 mmHg, a pulse of 126/min and a generalised seizure in the emergency department. His ECG shows a QRS duration of 142 milliseconds with a terminal R wave in lead aVR. Which one of the following is the most appropriate immediate treatment?