Herpes simplex virus infections practice

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General Practice and Population Healthcommon

A 29-year-old woman presents with painful genital lesions that began as small blisters 3 days ago. She describes burning on urination and has bilateral tender inguinal nodes; examination shows several shallow ulcers and a few intact vesicles on the vulva. She has no previous similar episodes and no generalized rash or painless ulcer. Which investigation is most appropriate to confirm the diagnosis?