Skin Cancer practice

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Dermatologycommon

A 52-year-old fair-skinned man who worked outdoors for 30 years presents because his wife noticed that a mole on his upper back has changed. It is now 8 mm across, asymmetrical with an irregular edge, and contains dark brown, black and a small pinkish area. It has been itchy but has not bled. He has no palpable lymph nodes. Dermoscopy shows an atypical network with irregular blotches and a blue-white structure.

Which one of the following is the most appropriate next step?