Emergency and Toxicologycommon
A 21-year-old man collapses at the 14 km mark of a city fun run on a 34°C day. In the trackside medical tent he is confused and agitated with a Glasgow Coma Scale score of 13 and hot, flushed skin. His rectal temperature is 41.4°C, heart rate 132/min, blood pressure 102/58 mmHg and respiratory rate 26/min. His airway is patent; he is moved into the shade and his clothing is removed. Which one of the following is the most appropriate immediate management?