Paediatricsmiddle twist
A 28-year-old woman who has had type 1 diabetes since she was twelve asks how to prepare for a pregnancy she hopes to start in about six months. Her most recent HbA1c is 8.4 per cent (68 mmol/mol) and she uses insulin glargine and insulin aspart. She has had no previous pregnancy, there is no family history of neural tube defects, her body mass index is 24 kg/m2 and she takes no other medicines. Which one of the following folate regimens should you recommend?