A 31-year-old woman weighing 60 kg restarts sertraline 100 mg daily for recurrent depression. She is exclusive…

Question

A 31-year-old woman weighing 60 kg restarts sertraline 100 mg daily for recurrent depression. She is exclusively breastfeeding a healthy, thriving 4-month-old born at term. A lactation medicines service estimates that the infant receives about 0.03 mg/kg daily through breastmilk. She has read that antidepressants pass into milk and asks whether she should stop feeding or change the way she feeds. Which one of the following is the most appropriate advice about her feeding?

Accepted Answer

Continue breastfeeding with no change to the regimen

Answer

Alternate each breastfeed with an infant formula feed

Answer

Breastfeed only immediately before she takes each dose

Answer

Express and discard milk for four hours after dosing

Answer

Stop breastfeeding and change entirely to infant formula

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