A 15-year-old boy weighing 60 kg presents to a metropolitan emergency department six hours after swallowing fo…

Question

A 15-year-old boy weighing 60 kg presents to a metropolitan emergency department six hours after swallowing forty paracetamol 500 mg tablets in one go. He has vomited twice and is otherwise well. His serum paracetamol concentration, taken four hours after ingestion, is above the nomogram treatment line but less than twice it, and his liver biochemistry and international normalised ratio are normal. Intravenous access is established. Which one of the following acetylcysteine regimens should he be…

Accepted Answer

Acetylcysteine 200 mg/kg intravenously over 4 hours

Answer

Acetylcysteine 50 mg/kg intravenously over 4 hours

Answer

Acetylcysteine 100 mg/kg intravenously over 16 hours

Answer

Acetylcysteine 150 mg/kg intravenously over 15 to 60 minutes

Answer

Acetylcysteine 200 mg/kg intravenously over 16 hours

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