A term boy born by normal vaginal delivery after an uncomplicated pregnancy is noted by the midwife to be visibly jaundiced at 16 hours of age. He is feeding well and is otherwise well. His mother is blood group O RhD positive; this is her second child. The baby's blood group is A RhD positive and the direct antiglobulin (Coombs) test is positive. Results: total serum bilirubin 212 µmol/L (unconjugated), haemoglobin 142 g/L, reticulocytes 9%. The blood film shows spherocytes.
Which one of the following is the most likely cause of his jaundice?
Keep going — a set of ten like this one, one at a time.
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