A 66-year-old man with diffuse large B-cell lymphoma is receiving chemotherapy through a tunnelled central venous catheter. On day 8 he develops fever of 38.6°C, rigors and erythema with tenderness along the catheter tunnel. His blood pressure is 105/65 mmHg, and he has no respiratory symptoms or other source of infection. Which additional antimicrobial is most appropriate while cultures are being processed?
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