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A 74-year-old woman presents with severe pain in her left leg that began abruptly two hours ago while she was sitting watching television. She walks to the shops most days and has never had leg pain on walking. Her pulse is 112/min and irregularly irregular. The left leg is pale and cold below the mid-thigh; the left femoral pulse is palpable but the popliteal and foot pulses are absent, while the right leg has palpable pulses throughout. Sensation over the left foot is reduced. Which one of the following is the most likely diagnosis?

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