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A 58-year-old man is receiving his first dose of intravenous vancomycin for a surgical site infection, charted to run over 60 minutes. Twenty minutes into the infusion he develops flushing and itching over his face, neck and upper chest. His blood pressure is 124/78 mmHg, heart rate 92/min, respiratory rate 16/min and oxygen saturation 98% on room air; there is no wheeze, stridor, or swelling of the lips or tongue. Which one of the following is the most appropriate next step?

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