A 74-year-old man reports several months of fatigue and burning of his feet. He has a smooth, sore tongue and impaired vibration sense at both ankles. His haemoglobin is 92 g/L (130–180), mean cell volume 119 fL (80–100), serum vitamin B12 is 74 pmol/L (140–700), folate is normal and liver and thyroid tests are unremarkable. Antibodies to intrinsic factor are detected. Which one of the following is the most likely diagnosis?
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