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A 41-year-old woman has been stable on clozapine for 18 months but presents with fever, painful swallowing and malaise. Her temperature is 38.5°C and her absolute neutrophil count is 0.4 × 10^9/L (1.5–7.5); the white-cell count was normal one month ago. She has no focal chest findings and has not started another medicine. Which one of the following is the most appropriate immediate management?

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ClozapineAgranulocytosisDrug Emergency

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