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Mechanisms of disease

How disease happens — pathology, pharmacology, microbiology. 33 questions.

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A 45-year-old woman with diabetes mellitus presents with a painful, rapidly expanding area of redness on her thigh. She has a fever of 39°C (102.2°F) and hypote…

Year 1 · Mechanisms of disease · middle twist

A 65-year-old man presents with purple spots on his forearms and hands that appeared over the past few days. He denies pain, itching, or trauma. His medical his…

Year 1 · Mechanisms of disease · middle twist

A 39-year-old male presents to the emergency department with sudden onset of pleuritic chest pain that worsens with a supine position and relieves with leaning…

Year 2 · Mechanisms of disease · common

During an epidemiological study of a population of 100,500 people, 500 individuals were identified as existing cases of a certain disease. Over the course of on…

Year 4 · Mechanisms of disease · middle twist

Which of the following congenital abnormalities is most commonly associated with lithium use during pregnancy?

Year 4 · Mechanisms of disease · common

A patient who was recently diagnosed with cancer refuses chemotherapy, despite the physician recommendation. The physician respects the patient's decision. Whic…

Year 1 · Mechanisms of disease · common

Which of the following is the most common type of familial dyslipidemia associated with markedly elevated LDL cholesterol and a high risk of early cardiovascula…

Year 4 · Mechanisms of disease · common

Which of the following mediators plays a key role in pain sensitization by enhancing nociceptor activity?

Year 4 · Mechanisms of disease · common

What is the most common type of malignant tumor of the urinary tract?

Year 3 · Mechanisms of disease · common

A 7-year-old boy presents to the emergency department with his mother, who reports that he developed a sore throat in the morning, which has worsened throughout…

Year 3 · Mechanisms of disease · common

You are conducting a routine developmental assessment on Leo, a healthy 8-week-old infant who was born full-term. His parents are curious about his developmenta…

Year 3 · Mechanisms of disease · middle twist

You are assessing Lucy, a 20-month-old child, in a routine pediatric check-up. Her parents are concerned because Lucy is not yet forming clear words, although s…

Year 3 · Mechanisms of disease · common

A 25-year-old patient receiving acetylcysteine for immediate-release paracetamol poisoning develops a rash, urticaria, and flushing shortly after the infusion s…

Curtin CAT · Mechanisms of disease · middle twist