Medicine

A 46-year-old man develops jaundice, dark urine and exertional dyspnoea over several weeks. He has splenomegaly, a haemoglobin concentration of 78 g/L (130–170)…

A 30-hour-old boy develops jaundice and pallor. He is feeding reasonably well and has mild splenomegaly. His mother is blood group O positive and he is group B…

A 26-year-old man is referred for recurrent episodes of yellowing of the eyes, usually after intercurrent illness. He has no pruritus, abdominal pain or weight…

A 67-year-old man with alcohol dependence has mild withdrawal 10 hours after his last drink, with anxiety, tremor and nausea but no hallucinations or seizure. H…

A 59-year-old woman develops sharp central chest pain two days after an uncomplicated ST-elevation myocardial infarction. She says it is worse when she takes a…

A 34-year-old woman with schizoaffective disorder becomes restless, sweaty and confused six hours after venlafaxine was increased and tramadol was prescribed fo…

A 29-year-old woman requests emergency contraception four days after unprotected intercourse. She has a body mass index of 34 kg/m² and takes carbamazepine for…

A 48-year-old woman taking sotalol for paroxysmal atrial fibrillation has two brief episodes of collapse. The ECG monitor records recurrent bursts of polymorphi…

A 70-year-old man presents with dysuria, a slow urinary stream, and a feeling of incomplete emptying. Urinalysis shows leukocytes and nitrites. He is afebrile a…

A 21-year-old woman presents to the GP with urinary urgency, suprapubic discomfort, and dysuria. This is her third similar episode in the past year. She does no…

A 45-year-old woman presents with a painful, swollen, red area on her right forearm that developed over the past two days. She reports a minor cut from gardenin…

A 45-year-old woman with diabetes mellitus presents with a painful, rapidly expanding area of redness on her thigh. She has a fever of 39°C (102.2°F) and hypote…

A 65-year-old man presents with purple spots on his forearms and hands that appeared over the past few days. He denies pain, itching, or trauma. His medical his…

A 39-year-old male presents to the emergency department with sudden onset of pleuritic chest pain that worsens with a supine position and relieves with leaning…

During an epidemiological study of a population of 100,500 people, 500 individuals were identified as existing cases of a certain disease. Over the course of on…

Which of the following congenital abnormalities is most commonly associated with lithium use during pregnancy?

A patient who was recently diagnosed with cancer refuses chemotherapy, despite the physician recommendation. The physician respects the patient's decision. Whic…

Which of the following is the most common type of familial dyslipidemia associated with markedly elevated LDL cholesterol and a high risk of early cardiovascula…

Which of the following mediators plays a key role in pain sensitization by enhancing nociceptor activity?

What is the most common type of malignant tumor of the urinary tract?