Oesophagus, stomach and duodenum

A 34-year-old woman describes 18 months of intermittent difficulty swallowing. From the beginning both liquids and solids have been affected, and it is worse wh…

Clinical rotations · common

A 66-year-old man is admitted with melaena from a duodenal ulcer and undergoes successful endoscopic haemostasis. He has taken aspirin 100 mg daily since a myoc…

Clinical rotations · middle twist

A 54-year-old man presents with persistent heartburn and regurgitation despite six weeks of once-daily omeprazole. He has no dysphagia, weight loss, or anemia.…

Clinical rotations · middle twist

A 40-year-old woman presents with a 6-month history of intermittent upper abdominal discomfort described as postprandial fullness and occasional epigastric pain…

Clinical rotations · common

A 58-year-old man with a 3-year history of gastroesophageal reflux disease (GERD) undergoes an upper endoscopy for ongoing reflux symptoms. Endoscopy reveals a…

Clinical rotations · middle twist

A 58-year-old man is undergoing evaluation for chronic upper gastrointestinal symptoms. He reports longstanding retrosternal burning, especially at night and af…

Clinical rotations · common

A 61-year-old man presents to the emergency department with a 6-hour history of hematemesis and melena. He reports a long-standing history of osteoarthritis, fo…

Clinical rotations · common

A 68-year-old man presents to his general practitioner for a routine review of his medications. He has a history of osteoarthritis, for which he takes naproxen…

Clinical rotations · middle twist

What is the first-line pharmacologic treatment for gastroesophageal reflux disease (GERD)?

Clinical rotations · common

A 55-year-old with progressive difficulty swallowing solid foods over 4 months has no accompanying chest discomfort or unpleasant oral taste. Weight loss of abo…

Clinical rotations · common