Approach to the jaundiced patient

A 21-year-old university student notices yellowing of his eyes after several days of restricted food intake during examinations. He is otherwise well and has no…

Clinical rotations · common

A 26-year-old man is referred for recurrent episodes of yellowing of the eyes, usually after intercurrent illness. He has no pruritus, abdominal pain or weight…

Mechanisms of disease · niche

A 29-year-old woman is admitted with nausea, jaundice and right upper-quadrant discomfort. Her alanine aminotransferase is 9200 U/L (5–40), aspartate aminotrans…

Clinical rotations · middle twist

A patient presents with dark urine and pale stools. Laboratory tests show: Total bilirubin: 8 mg/dL (Reference range: 0.1 – 1.2 mg/dL) Indirect bilirubin: 1 mg/…

Clinical rotations · middle twist