Primary somatosensory cortex (postcentral gyrus, Brodmann areas 3, 1 and 2)

Cortex or muscle · contralateral homunculus

Third-order axons end in the postcentral gyrus, arranged as a sensory homunculus with the leg on the medial surface and the face and hand on the lateral convexity, with the lips and fingers over-represented. The cortex resolves the discriminative aspects of touch, such as localisation, texture and shape, rather than detecting the stimulus itself.

Traced from the start

  1. Cutaneous mechanoreceptors (Meissner, Pacinian, Merkel, Ruffini)Proprioceptors (muscle spindle, Golgi tendon organ, joint receptors)
  2. Fasciculus gracilis (medial dorsal column)Fasciculus cuneatus (lateral dorsal column)
  3. Nucleus gracilis and cuneatus to internal arcuate fibres (sensory decussation, caudal medulla)
  4. Nociceptors and thermoreceptors (free nerve endings)
  5. Dorsolateral tract of Lissauer and dorsal horn synapse (Rexed laminae I, II and V)
  6. Anterior (ventral) white commissure
  7. Medial lemniscusLateral spinothalamic tract (anterolateral system)Anterior spinothalamic tract (crude touch and pressure)
  8. Ventral posterolateral nucleus of the thalamus (third-order neurone) and thalamocortical radiation
  9. Primary somatosensory cortex (postcentral gyrus, Brodmann areas 3, 1 and 2)

Detail

Homunculus
Leg medial (anterior cerebral artery); face and hand lateral (middle cerebral artery)
Function
Localisation, two-point discrimination, stereognosis, graphaesthesia

When it goes wrong

Parietal cortical lesion (middle cerebral artery stroke, tumour)

Cortical sensory loss: astereognosis, agraphaesthesia, impaired two-point discrimination and sensory extinction on double simultaneous stimulation, with pinprick, temperature and vibration relatively preserved

Anterior cerebral artery infarct

Contralateral leg sensory loss with leg-predominant weakness

Practise this structure

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