A healthy adult receives an intravenous glucose load. Plasma glucose is 12 mmol/L (reference 3.5–7.8 mmol/L), the measured glomerular filtration rate is 120 mL/min, and urine glucose is 2.0 mmol/L. The filtered glucose load is therefore approximately 1440 μmol/min. Which renal mechanism best explains the glucosuria?
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