A 4-year-old girl has had puffy eyelids each morning for two weeks and now has swollen legs and a distended abdomen. Her blood pressure is 96/58 mmHg. Urine testing shows protein 4+ and no blood, and microscopy shows no red cells or casts. Her urinary protein is almost entirely albumin. Plasma albumin is 16 g/L and creatinine 32 micromol/L.
A defect in which one of the following components of the renal corpuscle best accounts for this girl's urinary findings?
Keep going with ten more like this one.
Practise moreMore from Physiology
See allA 46-year-old man attends the clinic nine months after cardiac transplantation. He feels well, has no chest pain and walks four kilometres most days. He takes n…
Foundations · middle twist
A 24-year-old man presents with two hours of palpitations. He is alert, has no chest pain, and his blood pressure is 124/76 mmHg. The radial pulse is regular at…
Foundations · common
A 22-year-old woman is brought to the emergency department 30 minutes after an argument at home, breathing rapidly and deeply. She complains of tingling around…
Foundations · middle twist
A 43-year-old man is brought in 18 hours after a meal that included home-bottled vegetables. Over the past six hours his eyelids have drooped, his vision has do…
Foundations · middle twist
A 58-year-old man is freed after six hours trapped beneath a collapsed brick wall. He is alert, and both thighs are swollen and tender. He reports tingling in b…
Foundations · middle twist